Amplify energy & invigorate brain power
NAD+ is a powerful regenerative coenzyme that supports cellular energy production, brain health, and healthy aging from the inside out. Found in every living cell and playing a foundational role in energy metabolism, DNA repair, and mitochondrial function; levels decline naturally with age, making physician-prescribed NAD+ therapy an increasingly valuable tool for maintaining vitality and cognitive clarity.
Administered as an intramuscular injection for maximum bioavailability, RegenMD's NAD+ therapy is prescribed as part of a personalized protocol tailored to your energy, cognitive, and longevity goals.
The information provided on this page is for general informational purposes only and is not a substitute for professional medical advice. Always follow your RegenMD provider’s precise prescription and consult them directly with any questions or concerns. Not all patients qualify for every treatment—book a consultation to determine the best option for you.
NAD+ is administered as a intramuscular injection (IM), with a 28G/29G syringe at the prescribed dosage.
NAD+ (nicotinamide adenine dinucleotide) is one of the most important coenzymes in the human body, present in every cell and essential to hundreds of metabolic processes. It serves as a critical driver of cellular energy production, a key activator of proteins involved in DNA repair, and a regulator of biological processes tied to how we age, think, and feel. The challenge is that NAD+ levels decline significantly with age; by middle age, most people have roughly half the NAD+ levels they had in their twenties. This decline is associated with reduced energy, slower cellular repair, and diminished cognitive sharpness.
At the cellular level, NAD+ fuels the mitochondria by acting as an electron carrier in the process of converting nutrients into ATP, the body's primary energy currency. Higher NAD+ levels mean more efficient mitochondrial function, which translates directly into sustained energy production throughout the day. NAD+ also activates a family of proteins called sirtuins, which regulate cellular stress responses, inflammation, and the repair of damaged DNA. Sirtuins have been widely studied for their connection to healthy aging and longevity.
Beyond energy and repair, NAD+ plays a significant role in brain health. It supports the production of neurotransmitters involved in focus, memory, and mood, and protects neurons from oxidative stress. Many patients report improvements in cognitive clarity, mental sharpness, and overall sense of vitality as NAD+ levels are restored.
At RegenMD, NAD+ is administered as an intramuscular injection using a 28G/29G syringe, delivered Monday, Wednesday, and Friday over a five or ten-week program. Intramuscular delivery bypasses the digestive system, ensuring full absorption compared to oral NAD+ supplements, which degrade significantly before reaching the bloodstream. Your provider personalizes your protocol and monitors your response throughout.
NAD+ (nicotinamide adenine dinucleotide) is a naturally occurring coenzyme that powers energy production, DNA repair, and mitochondrial function at the cellular level. Levels decline significantly with age, and injectable NAD+ therapy is one of the most direct ways to restore them. RegenMD prescribes NAD+ as an intramuscular injection for maximum absorption, administered Monday, Wednesday, and Friday over a five or ten-week protocol.
NMN (nicotinamide mononucleotide) and NR (nicotinamide riboside) are precursor molecules the body must first convert into NAD+ before they become active. Most oral supplements use these precursors because NAD+ itself degrades in the digestive tract before reaching the bloodstream. Injectable NAD+ bypasses that conversion entirely, delivering the active coenzyme directly into circulation for immediate cellular use.
Rather than spiking after a single injection, cellular NAD+ levels build progressively across the protocol. Most patients notice compounding improvements in energy and mental clarity as the program advances. Following the initial program, maintenance injections help sustain elevated levels; without them, levels will gradually decline again over time.
NAD+ fuels neuronal energy metabolism, activates sirtuin proteins that protect brain cells from oxidative damage, and supports neurotransmitter synthesis involved in focus and mood. When cellular NAD+ is depleted, neurons become less efficient and more vulnerable to stress. Restoring adequate levels supports sharper thinking, faster recall, and more consistent concentration throughout the day.
Yes; NAD+ operates at the foundational cellular level, making it complementary to a wide range of other therapies. It pairs particularly well with mitochondrial support protocols, Sermorelin, and GLP-1 therapy. Your provider will assess your full health picture and recommend the most effective combination for your specific goals.
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