In the Mood peptide blend, a clear liquid inside a bottle against a dark grey background.
A loving couple holds each other in an intimate way to indicate improved libido and energy.
In the Mood peptide blend, a clear liquid inside a bottle against a dark grey background.
A loving couple holds each other in an intimate way to indicate improved libido and energy.
Ignite & Arouse

In the Mood

Enhance libido & increase energy

In The Mood is a peptide that enhances libido, increases satisfaction during sexual experiences, and restores confidence in intimate wellness. It uses PT-141 (bremelanotide); an FDA-approved active ingredient that works directly on the central nervous system by activating melanocortin receptors in the brain, unlike approaches that target the vascular system.

Beyond its primary benefits, PT-141 also supports mood regulation, stress reduction, and overall energy levels; making it a comprehensive solution for those looking to restore or elevate their intimate wellness.

In the Mood
  • Improves sex drive for those with low libido
  • Helps increase sexually satisfying experiences
  • Unlike Viagra® and other related medications, it does NOT act upon the vascular system
  • Increases energy
  • Beneficial for erectile dysfunction
  • Improved confidence and self-esteem
  • Reduces stress and improves mood
  • Stimulates the immune system
  • Potentially lower blood pressure
  • Decreased fat storage
  • PT-141
  • 5-10IU SubQ
  • Monday-Friday (a.m.)
  • 4 weeks

In The Mood is administered as a subcutaneous (SubQ) injection, with a 30G/31G syringe at the prescribed dosage.

Injection Tutorial

How In the Mood Works

In The Mood is powered by PT-141, also known as bremelanotide, an FDA-approved peptide that takes a fundamentally different approach to supporting sexual health. Where many traditional options work by targeting blood flow through the vascular system, PT-141 operates upstream—directly activating melanocortin receptors in the brain that regulate sexual arousal and desire. This central nervous system mechanism means it addresses the neurological root of low libido rather than simply managing a physical response.

PT-141 works by binding to melanocortin receptors—specifically MC3R and MC4R—in the hypothalamus, a region of the brain that plays a central role in regulating sexual behavior, mood, and energy. By activating these receptors, PT-141 signals the brain to increase sexual desire and arousal naturally, without relying on hormonal changes or vascular intervention. This makes it a viable option for both men and women experiencing reduced libido, regardless of whether the underlying cause is hormonal, psychological, or situational.

In addition to its primary libido-enhancing effects, PT-141 supports mood regulation and stress reduction through its action on the melanocortin system, which is also involved in the body's broader emotional and energy regulation pathways. Many patients report improved confidence, elevated mood, and increased energy alongside its primary benefits.

At RegenMD, In The Mood is prescribed as a subcutaneous injection administered with a 30G/31G syringe at your individualized dosage. The standard protocol runs Monday through Friday over a four-week program, with dosing personalized to your response and wellness goals. Your provider monitors your progress throughout and adjusts the protocol as needed.

What This Means For You

  • Enhanced sexual desire and arousal
  • Increased sexual satisfaction and confidence
  • Works on the central nervous system, not the vascular system
  • Supports mood regulation and stress reduction
  • Increased energy levels
  • Effective for both men and women
  • Personalized dosing monitored by a licensed provider

Frequently Asked Questions

In The Mood is made with PT-141, also known as bremelanotide. This ingredient is an FDA-approved synthetic peptide derived from a melanocortin analog originally studied for skin pigmentation. Researchers discovered it had a pronounced effect on sexual arousal through its action on melanocortin receptors in the brain, leading to its development as a therapeutic for low libido in both men and women. Unlike most sexual health treatments, it works on the central nervous system rather than the vascular system.

Testosterone therapy addresses libido by restoring hormonal levels that may have declined due to age or deficiency. PT-141 works independently of hormone levels, activating melanocortin receptors in the brain that directly regulate sexual desire. The two can be complementary; patients with both hormonal deficiency and neurological libido dysfunction may benefit from a combined approach. Your RegenMD provider will assess which is most appropriate for your specific situation.

PT-141 typically begins taking effect within 45 minutes to an hour of subcutaneous administration. Effects generally last several hours. Unlike daily hormonal therapies, the response is relatively immediate, making timing of administration an important part of the protocol.

PT-141 can be used situationally rather than on a fixed daily schedule, which distinguishes it from many other peptide therapies. RegenMD's standard protocol runs Monday through Friday over four weeks to establish a therapeutic baseline, after which usage can be adjusted based on your response and lifestyle. Your provider will guide the transition from the initial protocol to ongoing use.

PT-141 was originally FDA-approved specifically for premenopausal women with hypoactive sexual desire disorder (HSDD), making it one of the few treatments with clinical evidence specifically in women. It works by activating melanocortin receptors in the hypothalamus, which regulate sexual desire independently of estrogen or testosterone levels. This makes it effective even when hormonal levels are within normal ranges but libido remains low.

Getting Started Is Easy

Step 1: Consultation

A consultation to explore your goals, answer questions, and outline your wellness plan.

Step 2: Evaluation

Meet with a provider for a personalized evaluation and tailored peptide treatment plan.

Step 3: Activation

Finalize your order, receive treatment details, and begin your wellness journey.